Australian and New Zealand Society of Nephrology

Research Opportunity

Sir Charles Gardner Hospital - Department of Nephrology

Our nephrology group consists of 7 Nephrologists, all of whom have an active interest in nephrology research. There is an established track record within this group with both grant success and publications. Nephrologists with this group are also members of the majority of key committees around Australia and New Zealand. There is a tight link between SCGH and the University of Western Australia with one of the Nephrologists having a full-time academic appointment and laboratory facilities being available on site in SCGH. The research unit is supported by two Research Coordinators and a Research Nurse, and currently has 4 PhD students.

Basic Science Research

1. General Nephrology, CKD and Dialysis
• Collaborative links have been established with a very strong mesothelial research group within the UWA to investigate peritoneal membrane function and the effect of infection.
2. Transplantation
• Effect of Vitamin D on immune function (in vitro studies)
• Immune responses by virus specific T-cells;

Clinical Science Research

1. General Nephrology, CKD and Dialysis
• Comparing nurse and doctor-led multidisciplinary CKD clinic models
• QOL assessment in CKD management/conservative versus active management in the elderly
• Vitamin D in CKD stages 3-5
• Cardiovascular risk factor modification in CKD – inflammation and insulin resistance
• Prognostic significance of highly sensitive troponin assays in dialysis patients
• Role of anti-Xa monitoring for anticoagulation in CKD patients
• Incentive-driven dietary phosphate modification by patients on dialysis
• Identification of primary versus secondary membranous GN
• Determinants of drug-induced renal injury
• EPO-receptor and responses to EPO
2. Transplantation
• Role of acceptable HLA-mismatches in highly-sensitised renal transplant candidates
• MMF pharmokinetics
• Conversion to mTORs – effect on immunological and non-immunological risk factors
• Immune modulation in ECD recipients
• Glucose dysregulation post-transplant
• Cardiovascular risk factor modification post –transplantation
• Anti-viral immune responses post transplant
4. Epidemiology
• Strong links with ANZDATA committees with a track record of contributing to ANZDATA publications

Contacts

Professor Neil Boudville
P :
F :
E : Neil.boudville@uwa.edu.au

Dr Aron Chakera
P :
F :
E : aron.chakera@health.wa.gov.au

Dr Doris Chan
P :
F :
E : doris.chan@health.gov.au

Dr Sharan Dogra
P :
F :
E : sharan.dogra@health.wa.gov.au

Dr Wai Lim
P :
F :
E : wai.lim@!health.wa.gov.au

Dr Hadley Markus
P :
F :
E : hadley.markus@health.wa.gov.au

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